Curry, Stephen H.

Introduction to drug disposition and pharmacokinetics / Stephen H. Curry, Robin Whelpton. - Chichester, U.K. : John Wiley & Sons, 2017. - xi, 323 p. : ill., charts.

Introduction: basic concepts -- Drug administration and distribution -- Drug metabolism and excretion -- Single-compartment pharmacokinetic models -- Multiple-compartment and non-compartment pharmacokinetic models -- Kinetics of metabolism and excretion -- Clearance, protein binding and physiological modelling -- Quantitative pharmacological relationships -- Pharmacokinetics of large molecules -- Pharmacogenetics and pharmacogenomics -- Additional factors affecting plasma concentrations -- Effects of age and disease on drug disposition -- Drug interactions and toxicity -- Perspectives and prospects: reflections on the past, present and future of drug disposition and pharmacokinetics.


9781119261049 (pbk.)

Pharmaceutical preparations--Metabolism

QV38 / C976I 2017