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Applied biopharmaceutics & pharmacokinetics / editors, Leon Shargel, Andrew B.C. Yu.

Contributor(s): Shargel, Leon | Yu, Andrew B. C.
Call number: QV38 A652 2016 Material type: materialTypeLabelBookPublisher: [Singapore] : McGraw-Hill Education, 2016. Edition: 7th ed., International ed.Description: xvii, 910 p. : ill., charts.ISBN: 9789814670241 (pbk.).Subject(s): Biopharmaceutics | Drug administration routes | Models, Chemical | Pharmacokinetics
Introduction to biopharmaceutics and pharmacokinetics -- Mathematical fundamentals in pharmacokinetics -- Biostatistics -- One­compartment open model: intravenous bolus administration -- Multicompartment models: intravenous bolus administration -- Intravenous infusion -- Drug elimination, clearance, and renal clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics and drug metabolism -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and In Vitro drug product performance -- Drug product performance, In Vivo: bioavailability and bioequivalence -- Biopharmaceutical aspects of the active pharmaceutical ingredient and pharmaceutical equivalence -- Impact of biopharmaceutics on drug product quality and clinical efficacy -- Modified-release drug products and drug devices -- Targeted drug delivery systems and biotechnological products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Application of pharmacokinetics to specific populations: geriatric, obese, and pediatric patients -- Dose adjustment in renal and hepatic disease -- Empirical models, mechanistic models, statistical moments, and noncompartmental analysis.
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หนังสือทั่วไป CL_Pharmacology_General Book QV38 A652 2016 (Browse shelf) Checked out 23/02/2020 1 1000185783

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